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The Psyche Deli's avatar

Great article as always! What would be your thoughts on wether the duration of NN-DMT could be extended by pindalol or some other beta blocker or other molecule? Wondering if the subjective experience would differ from extending the state via MAO inhibition….

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entropy labs's avatar

beautifully written.. "psychedelicy" 🤌🏼

I have even been thinking about the other less talked about receptors.. for instance.. should we also minimize activation of the 5HT2B receptor in this cocktail? Or should we just add a 5HT2B antagonist? I love the example of 5-MeO vs N,N but I often wonder what is happening with the other 14 receptors? This is a very promising strategy for "removing the trip" but I wonder if the neurobiology is still the same? Would a dampened trip still have the beneficial neuroplasticity?

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