34 Comments

It's almost hard to believe reading this. I would have thought there'd be many psychonauts out there on the nexus and DMT reddits that would have given this a go and reported on it. Well if there wasn't before, I am sure there will be now.

Nice to see you back on here again too, mate!

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Yeah, it's strange, since Ott's (and others) experiments were way back in the late 90s. I think everyone became entranced by the "ayahuasca effect" and just assumed a single plant decoction would be impossible..

(I'm currently writing a new book on DMT, so writing time otherwise is more patchy!!)

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Ooh! Can't wait to read it :D

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No way

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Others like De Rio’s, R. Metzner, J. Bigwood.

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Success!! Did it and it worked. Let me start by saying that I know several changes that I will make to ensure better results next time. I used 30g of powdered mimosa bark and 125ml of filtered water. Soaked twice and strained through a paper coffee filter. 

The solution was mixed in an AG1 drink container which didn't have a lot of surface area so I'll use a bigger container next time. Also, when trying to squeeze the mixture the coffee filter broke and a little of the powder fell into my glass. I already have a better filter for next time.

Onset happened at about an hour. Unfortunately, I had just given up and eaten a sandwich and gone to bed. Once I got in bed I started to notice fantastic geometric sharp pointed images with small caption boxes filled with scrolling letters and numbers. It was all gibberish yet I seemed to understand some meaning from it. 

There was no nausea or sickness of any type. I did notice a feeling in my head and stomach at times but it wasn't unpleasant. The taste wasn't great but I've had worse. I didn't use any honey or any sweetener but I may use it next time.

On the next attempt I'll double the dosage and be more patient. 

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Wonderful! Ott was right! :)

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Yes indeed!! I’ll make another attempt in a fortnight and post updated results. I was a little embarrassed about how I ate and went to bed but was still excited to share the positive results. Thank you so much for sharing that info. Very excited to hear about your new book!!

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No effect for me.

25g ground + 125ml filtered water > 24 hour soak with stirs > tea strainer > filtered with coffee paper > drank after 13 hours overnight fast.

The tannins make it hard to drink (like really strong black tea) so I used a straw to bypass my tongue.

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I have read somewhere in the DMT literature that a small percentage of the population do not react to any form of DMT and like yourself this brew did nothing for me.

An odd question, do you have a condition known as aphantasia?

I ask, as this is also a condition that effects only a small percentage of the population and normally goes unrecognised and it is associated with brain induced images. I was in my late 50's before coming across aphantasia and understanding I too had this condition.

Given the main characteristic of aphantasia is an inability to visualise objects in the minds eye I wonder if there is any connection.

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wow its interesting, I too have aphantasia, and have tried ayahuasca twice without having noticeable changes in perceptible experience.

tried DMT and yeah, I did have one big journey there, it was my first psychedelic, so its going to be interesting to try now with this method, to see if there's a pattern between aphantasia and the effect on these experiences

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No aphantasia that I'm aware of but maybe I don't react; I've got plenty of bark left so I'm trying methanol extraction with rue - no effect yet but started with small amount.

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Out of curiosity have you had other pshychedelic experiences and this just this one method did not work or?

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Maybe try a folk extraction with red wine - evidently, this is how some of the Brazilian cults do it - the info I read said to leave it for a few days - but when I extract herbs or flowers in a folk extraction I usually leave it in a dark place, turning it every few days for a month. This works beautifully with Blue Lotus...

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I literally could not stop reading this. Like a mystery story, but without a solution to the mystery. It seems that there must be one or more compounds with MAO inhibitory activity in there somewhere. It's just a question of funding them.

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You got me at vomiting and shitting. But wow. Just wow.

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I am very interested to learn more about the recipe of that "Reality Sandwich" you are mentioning :-p.

Joke aside, great and informative article as always Andrew!

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Sounds so simple. Why aren’t more people trying this? Thanks for the knowledge revival!

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Fascinating! I wonder why this isn't more widely known? It seems to fit right between the brief roller coaster of smoked DMT and the long expeditions of Ayahuasca/LSD/fungi...

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Thank you, you are remarkable. Fabulous research as always. Strangely, I have have some of this dye in my pantry.

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Ayahuasca analogue is a misnomer here. An orally active DMT concoction, yes. But it isn't comparable to ayahuasca, beyond perhaps some overlap in the visionary realm. As I know you know, ayahuasca is the name of the vine itself, as well as the brew. That isn't likely happenstance. The vine is held in esteem for its own properties, and is used by some groups without any admixture constituents. The purgative characteristics of the vine are considered an important and valuable element in working with this plant. I think "Businessman's Ayahuasca" as a title is taking some poetic liberty to give a sense of what the article describes, and that seems ok. But to then refer to it as an ayahuasca analog misses the mark. For someone who writes with your precision, in my opinion, you ought not call it that.

Aside from this squeaking, I offer deep bows for all the work you do. Love the books and stoked to hear another one is in the works.

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This time, your squeaking is good squeaking. I agree, "oral DMT" is better than "ayahuasca analogue" which is a bit of a misnomer. Title changed! (You can put this on your CV)

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A most generous offer. LinkedIn profile updated with "Substack subtitle editor for Dr Andrew Gallimore"

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Tried it yesterday. Tasted unbelievably horrid. Did not have a notable effect, felt a little bit spacey and chill, but that could have been placebo, or just hunger and tiredness. Either way, excellent article 🫡.

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Gave this a try last night. Wasn’t very “scientific” about it since I had no scale, no filtered water etc. No coffee grinder either. So, just took a decent amount of bark, put it in a Tupperware with clean water (tap water in my country is high quality) then proceeded to use a mixer/blender (the kind you use to blend your soup) in the mixture to break up the bark. I let it sit for 48 hours. Strained it through a coffee filter. I tried a sip and realized you definitely need to put honey as its taste is utterly disgusting, (memories of my ayahuasca came bubbling up). I downed a small coffee mug of the stuff and waited. After about 20 minutes I began feeling the “heavy” feeling I often experienced on psychedelics, not much else happened. I decided to go to bed, while lying in bed I definitely felt “something” but no major visuals or full psychedelic experience. I did have an amazing sleep though, feeling extremely rested and relaxed.

Maybe I’ll try a bigger mug next time. Or, get more

“Scientific” and follow the instructions in terms of quantity and volume.

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Very interesting

I do however see a potential microbiological risk.

Any views on the effect of pasteurising the bark by using 70-80 C water?

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A thought I had is that maybe some people have their MAO inhibited all the time through their normal diet, and these people don't need an extra MAO inhibitor. Curcumin, found in turmeric, is a MAO inhibitor, for example. Many foods seem to contain MAO inhibitors. Tobacco also contains MAO inhibitors.

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It's possible that diet could have an influence, as could the particular variants of MAO that different people carry. Those with particularly active variants might struggle to achieve effects with this simple water extract, whereas those with less active variants might do better.

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Dear Andrew,

I am a big fan of your work and absolutely love reading your posts. You have such an incredible insight and passion and I admire your craft very much. I am an aspiring writer and researcher and would be honored if you, or anyone, took the time to read my latest post where I discuss trauma, recovery and a bit of my own journey on this planet. You can find it here if interested:

https://open.substack.com/pub/astralprojections/p/fatal-progression?r=32c52d&utm_campaign=post&utm_medium=web

My apologies if this is not the proper way to network as I am very new to this platform. Keep up your solid work!

Warmly,

S. J. Perkins

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Huge disappointment! I followed the instructions to the letter and 70 mins in nothing!

The brew tasted utterly vile so I would keep the honey until afterwards has been drunk if you are going to give this a try.

Once I got the brew down there was no nausea or upset stomach just flushing to the face and a slight headache, but other than that nothing!

Aw well back to the drawing board!

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Wow! Fascinating. And I’m indeed interested in exploring further.

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